Neuroleptic Malignant Syndrome After Exposure to Asenapine: A Case Report.

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Neuroleptic malignant syndrome is a serious side effect of antipsychotic medications that occurs in up to 2% of those receiving neuroleptics. Asenapine is a newly available second-generation antipsychotic. This case report should remind all clinicians that all antipsychotics, whether first or second generation, have potential for this serious side effect. Clinicians utilizing asenapine must remember this potential side effect that is found in all agents in this class of drug.