Gastrointestinal Disorders

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Diseases of the gastrointestinal (GI) system are prevalent and are frequently associated with distress and psychiatric disorders, which may cause, exacerbate, or be a reaction to these disorders (Jones et al. 2007; Sandler et al. 2002). In this chapter, we review the use of psychotropic medications in the treatment of GI disorder symptoms and comorbid psychopathology, potential interactions between GI medications and psychotropic agents, risks of prescribing psychiatric medications in the presence of particular GI disorders, and alterations in the pharmacokinetics of psychotropic drugs induced by GI disorders (e.g., hepatic failure, short bowel syndrome). The chapter is organized first by organ system and then by specific GI disorder.